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cf catalog 7570 gh 005 r d systems  (R&D Systems)


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    R&D Systems cf catalog 7570 gh 005 r d systems
    Cf Catalog 7570 Gh 005 R D Systems, supplied by R&D Systems, used in various techniques. Bioz Stars score: 94/100, based on 29 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/cf+catalog+7570+gh+005+r+d+systems/Recombinant+Human+Active+Heparanase%2FHPSE+Protein%2C+CF/pmc12276975-978-5-9
    Average 94 stars, based on 29 article reviews
    cf catalog 7570 gh 005 r d systems - by Bioz Stars, 2026-10
    94/100 stars

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    Recombinant:

    Article Title: Could Hydrophobicity of Sulfated Pseudo-Trisaccharides Derived from Repurposing Aminoglycoside Tobramycin Modulate the Enzymatic Activity of Heparanase?
    Article Snippet: .. Recombinant human active heparanase/HPSE protein, CF (Catalog #: 7570-GH-005, R&D Systems), tris-buffer (contains 20 mM TrisHCl, 0.15 M NaCl, and 0.1% CHAPS, pH 7.5), biotin-heparan sulfate-Eu cryptate (Cisbio, Cat #: 61BHSKAA), streptavidin-XLent! (Cisbio, Cat #: 611SAXLA), dilution buffer (contains 0.1 M NaH2PO4, 0.8 M KF, 0.1% BSA, pH 7.5 and 2 mg/mL), sodium acetate buffer (NaOAc, pH 5.5, 0.2 M), 96-well microplates (Corning #3693 96 well, white polystyrene, half-area). .. Different concentrations of HS mimetic (9.0 μ L) or suramin (IC 50 5.0–10 μ M, used as positive control) were prepared in labeled protein LoBind vials (Eppendorf).

    Article Title: Could Hydrophobicity of Sulfated Pseudo-Trisaccharides Derived from Repurposing Aminoglycoside Tobramycin Modulate the Enzymatic Activity of Heparanase?
    Article Snippet: Heparanase (HPSE) remodeling of the extracellular matrix makes it a crucial therapeutic target.. The development of effective glycan-based HPSE inhibitors has been limited by bleeding and thromboembolic disorders.. In this report, we present a structure-based design approach that rapidly generates a library of potent and selective HS mimetics, synthesized in 8 to 9 steps from readily available aminoglycoside tobramycin.



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